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January 2021

Hepatoprotective Activity of Leaves of Pongamia pinnata In CCl4 Induced Hepatic Model

  • Manjunath C*, Dinesh M, Karigar AA, Joshi VG, Sikarwar MS

Journal of Life Science and Biotechnology ,Volume 2021 , Page 102-105
Published 1 January 2021

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Abstract





The liver is an organ of utmost importance, which plays a vital role in the metabolism of drugs entering the body. A variety of drugs and plant extracts were evaluated for their hepatoprotective activity. Present study was undertaken to ascertain the hepatoprotective effect of dried leaves of Pongamia pinnata. Chloroform and ethanolic extract of dried leaves of Pongamia pinnata was evaluated and subjected for hepatoprotective activity in two doses of 250mg and 500mg in wistar strain of albino rats against CCl4 induced hepatic damage. SGOT, SGPT, ALP and total Bilirubin were used as biochemical marker for assessment of the activity. The Chloroform     500 mg and ethanolic extract 250 mg has found significant hepatoprotective activity by virtue of lowering the marker enzymes like SGPT, SGOT and ALP.





Keywords:
  • Pongamia pinnata, Hepatoprotective activity, SGOT, SGPT, ALP, Bilirubin, CCl4
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How to Cite

Karigar AA, Joshi VG, Sikarwar MS, M. C. D. M. (2021). Hepatoprotective Activity of Leaves of Pongamia pinnata In CCl4 Induced Hepatic Model. Journal of Life Science and Biotechnology, 102–105. Retrieved from https://everant.in/index.php/jlsb/article/view/552
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    Journal of Life Science and Biotechnology
    ISSN : 2456-1061
    Journal of Life Science and Biotechnology