Abstract

The liver is an organ of utmost importance, which plays a vital role in the metabolism of drugs entering the body. A variety of drugs and plant extracts were evaluated for their hepatoprotective activity. Present study was undertaken to ascertain the hepatoprotective effect of dried leaves of Pongamia pinnata. Chloroform and ethanolic extract of dried leaves of Pongamia pinnata was evaluated and subjected for hepatoprotective activity in two doses of 250mg and 500mg in wistar strain of albino rats against CCl₄ induced hepatic damage. SGOT, SGPT, ALP and total Bilirubin were used as biochemical marker for assessment of the activity. The Chloroform     500 mg and ethanolic extract 250 mg has found significant hepatoprotective activity by virtue of lowering the marker enzymes like SGPT, SGOT and ALP.